In addition to solid coverage of the core English vocabulary, including new words and senses, with definitions that are concise and easy-to-understand, theOxford American Large Print Dictionary also includes thousands of difficult and literary words that are most often looked up. It also includes short, accessible notes on difficult spellings, confusable words, and tricky areas of usage.

The book's clear page layout, designed in association with Lighthouse International, offers enlarged fonts, larger margins, generous linespacing, and good quality paper, ensuring that there is a minimum of glare and show-through.
All Oxford American dictionaries use an easy-to-use respelling system to show how entries are pronounced. It uses simple, familiar markings to represent common American English sounds.